Monday, March 31, 2008

Sjogren's Syndrome





  • Sjogren's ( show grins) syndrome is an autoimmune disorder that is often accompanied by a connective tissue disorder such as rheumatoid arthritis or lupus. The cause is unknown, but factors such as heredity, hormones, infection, and the nervous system can play a part. With this syndrome, the white blood cells attack the moisture producing glands, and in rare cases may even damage lungs, kidneys, and liver. If you have primary Sjogren's, then there is no direct cause, but if you have secondary Sjogren's then it may be from another disease.

    This syndrome is hard to diagnose because it mimics other diseases and medication side effects. However, it is more common in women, especially over the age of 40. Signs and symptoms include:


  • dry eyes and mouth


  • dental cavities


  • fatigue


  • enlarged parotid gland


  • difficulty swallowing/chewing


  • change in sense of taste


  • hoarseness


  • oral yeast infections


  • skin rashes or dry skin


  • vaginal dryness


  • dry, non productive cough


  • joint pain, swelling, and stiffness

There are different screening tests to diagnose Sjogrens. These include, blood test, eye test, imaging (sialogram, salivary scintigraphy, and chest xray), biopsy, urine sample, and slit lamp exam.

Complications are similar to symptoms, but in rare instance people may develop lymphoma, and peripheral nervous system disorders.

There is no cure, but you can treat the symptoms with a variety of medication. Surgery is sometimes and option. It is also important to increase fluid intake, use of moisturizers, eye drops, and nasal sprays, and have increased humidity.

Sources:

mayoclinic.com

www.orthop.washington.edu

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